THE FACT ABOUT NAD+ SUPPLEMENTATION AND MITOCHONDRIAL HEALTH THAT NO ONE IS SUGGESTING

7c,d). Inhibition of glycolysis altered neither replication fork progression nor the effects of NAD+ treatment, suggesting that glycolysis isn't a limiting variable for NAD+-induced effects on DNA synthesis. Phenocopying the effect of BPTES, oligomycin rescued the inhibitory effect of NAD+ treatment on fork speed partly in HeLa and completely in U2